“European Biological Variation Study (EuBIVAS): Sample collections from healthy volunteers from six European Labs for biological variation estimates’ update “

To address some of the concerns currently raised about the quality of the data available in published studies of biological variation, and to address the need to deliver new data using latest-generation analytical methods, the BV working group of the EFLM has designed the European Biological Variation Study (EuBIVAS). In this study, a bank of specimens collected from 91 healthy individuals from six European labs has been established to obtain robust and high-quality BV estimates for the highest possible number of measurands.

The main finding of the first step of EuBIVAS measurements is that most of within-subject and between-subject BV data are lower than those reported in the current on-line database, and, consequently, the analytical performance specification derived from them.