The role of laboratory in determination and management of anticancer therapies.

Aldo Tomasi, Tomris Özben, Monia Maccaferri, and Giovanni Ponti.

Malignancies, such as leukaemia, lymphoma, and myeloma but also many epithelial malignancies shed tumour cells into the circulating blood. The potential role of circulating tumour DNA shed by tumour cells into the plasma of cancer patients is becoming a prognostic and predictive tool for stratification, clinical management and follow-up of cancer patients leading to personalized prognosis and therapy.